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Inheritance of T helper immunodeficiency (thid) in LEC mutant rats

โœ Scribed by Takahisa Yamada; Takashi Natori; Keisuke Izumi; Tohru Sakail; Takashi Aguil; Kozo Matsumoto


Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
277 KB
Volume
33
Category
Article
ISSN
0093-7711

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Ontogeny of T cell maturation in LEC mut
โœ Takashi Agui; Tohru Sakai; Kozo Matsumoto ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 421 KB ๐Ÿ‘ 1 views

## Abstract LEC rats bear a congenital deficiency in CD4^+^CD8^โˆ’^ thymocytes and peripheral CD4^+^ T cells, and consequently a deficiency in T~h~ cell functions. Ontogeny of T cell maturation in normal and LEC mutant rats was, therefore, investigated. Prenatal development of thymocytes in normal ra