Bimodal regulatory effect of melittin an
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K Koumanov; A Momchilova; C Wolf
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Article
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2003
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Elsevier Science
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English
β 177 KB
Melittin and phospholipase A 2 -activating protein (PLAP) are known as efficient activators of secretory phospholipase A 2 (sPLA 2 ) types I, II, and III when phospholipid liposomes are used as substrate. The present study demonstrates that both peptides can either inhibit or activate sPLA 2 dependi