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Influence of opioids on β-receptors down-regulation: studies in cultured C6 glioma cells

✍ Scribed by A. Reggiani; A. Carenzi; D. Della Bella


Book ID
115797369
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
545 KB
Volume
423
Category
Article
ISSN
0006-8993

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C6 glioma cells possess beta adrenergic receptors coupled with adenylate cyclase which can be irreversibly blocked by bromoacetylaminomethylpindolol (Br-AAM-pindolol), a beta adrenergic antagonist. With 1 microM Br-AAM-pindolol, more than 80% of beta adrenergic receptors, labeled by (3H)-dihydroalpr