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Differential down-regulation of β1- and β2-adrenergic receptor mRNA in C6 glioma cells

✍ Scribed by Christopher Hough; De-Maw Chuang

Book ID
115763224
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
753 KB
Volume
170
Category
Article
ISSN
0006-291X

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C6 glioma cells possess beta adrenergic receptors coupled with adenylate cyclase which can be irreversibly blocked by bromoacetylaminomethylpindolol (Br-AAM-pindolol), a beta adrenergic antagonist. With 1 microM Br-AAM-pindolol, more than 80% of beta adrenergic receptors, labeled by (3H)-dihydroalpr