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Down-regulation of thyroid hormone nuclear receptor levels by l-triiodothyronine in cultured glial C6 cells

✍ Scribed by Ortiz-Caro, Javier; Montiel, Fatima; Yusta, Bernardo; Pascual, Angel; Aranda, Ana


Book ID
121930455
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
918 KB
Volume
49
Category
Article
ISSN
0303-7207

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Regulation of thyroid hormone receptor a
✍ B. Yusta; J. Ortiz-Caro; G. Bedo; A. Pascual; Ana Aranda πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 859 KB

Butyrate produced a biphasic modulation of the thyroid hormone receptor in neuroblastoma N2A cells increasing receptor number by 20-35 % at concentrations 0.25-0.75 mM and decreasing receptor levels by 3045% at 2 4 mM. The half-life of the receptor, as assessed by its disappearance after incubation