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Influence of inducers and inhibitors of cytochrome P450 on the hepatotoxicity of hydrazine in vivo

โœ Scribed by Andrew M. Jenner; John A. Timbrell

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
999 KB
Volume
68
Category
Article
ISSN
0340-5761

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D. melanogaster development was markedly retarded and its survival decreased by larvae treatment with compounds being strong inducers of the cytochrome P-450 2B in mammalsphenobarbital (PB\*), perfluorodecaline (PFD), transstilbene oxide (TSO), and triphenyldioxane (TPD). At the same time, the weak