𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Role of cytochrome P450 in hepatotoxicity induced by di- and tributyltin compounds in mice

✍ Scribed by S. Ueno; N. Susa; Y. Furukawa; M. Sugiyama

Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
367 KB
Volume
69
Category
Article
ISSN
0340-5761

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Crucial role of cytochrome P450 in hepat
Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats
✍ Yasuhiro Ishihara; Satomi Ishii; Yufu Sakai; Nobue Yamamura; Yukiko Onishi; Nori πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 482 KB

## Abstract Quinone toxicity is induced by two principal mechanisms: arylation/alkylation and a redox cycle. We have previously shown that increases in intracellular levels of superoxide anion and cell death induced by 2,3‐dimethoxy‐1,4‐naphthoquinone (DMNQ), a redox cycling quinone, are enhanced b

Induction of cytochrome P450 2E1 increas
Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice
✍ Xiaodong Wang; Yongke Lu; Arthur I. Cederbaum πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 511 KB

Cytochrome P450 2E1 (CYP2E1) may be a central pathway in generating oxidative stress, reactive oxygen species, and causing hepatotoxic injury by alcohol and various hepatotoxins. This study evaluated the ability of CYP2E1 to potentiate or synergize the hepatotoxicity of Fas in vivo. C57BL/6 mice wer

Differences in induction of hepatic cyto
Differences in induction of hepatic cytochrome p450 isozymes by mice in eight methylenedioxyphenyl compounds
✍ Lewandowski, Margaret ;Chui, Y. C. ;Levi, Patricia E. ;Hodgson, Ernest πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 900 KB

Eight methylenedioxyphenyl (MDP) compounds were examined for their ability to induce cytochrome P450 (P450) in mouse liver. Induction by safrole, isosafrole, and dihydrosafrole was studied in both C57BLl6N (Ah-responsive) and DBA/2N (Ahnonresponsive) male mice after IP administration of 200 mglkglda