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Influence of folate pathway polymorphisms on high-dose methotrexate-related toxicity and survival in childhood acute lymphoblastic leukemia

✍ Scribed by Erčulj, Nina; Kotnik, Barbara Faganel; Debeljak, Maruša; Jazbec, Janez; Dolžan, Vita


Book ID
120079113
Publisher
Informa plc
Year
2012
Tongue
English
Weight
239 KB
Volume
53
Category
Article
ISSN
1042-8194

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## Abstract ## Background Tromboembolic and hemorrhagic complications are significant causes of death in patients with malignancy. These are well‐known with the use of certain drugs. This study was planned to investigate whether there was any effect of high‐dose methotrexate on the hemostatic syst