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Influence of Dithiocarb, (+)-Catechin and Silybine on Halothane Hepatotoxicity in the Hypoxic Rat Model

✍ Scribed by Siegers, Claus-Peter ;Frühling, Andreas ;Younes, Maged

Book ID
114800204
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
326 KB
Volume
53
Category
Article
ISSN
0001-6683

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Influence of alcohol, dithiocarb and (+)-catechin on the hepatotoxicity and metabolism of vinylidene chloride in rats
✍ C.-P. Siegers; K. Heidbüchel; M. Younes 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 556 KB

## Abstract Hepatotoxicity of vinylidene chloride (1,1‐dichloroethylene, VDC) in rats was evidenced by increases of serum enzyme activities of the aminotransferases (GOT, GPT) and sorbitol dehydrogenase (SDH). Simultaneous treatment with ethanol (4.8 g kg^−1^ p.o.) totally inhibited these hepatotox