Influence of dissolved oxygen and shear conditions on clavulanic acid production byStreptomyces clavuligerus
β Scribed by J. C. Rosa; A. Baptista Neto; C. O. Hokka; A. C. Badino
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 293 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1615-7605
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A high concentration of potassium phosphate (75-100 mM) stabilized pH and supported extensive growth of Streptomyces clavuligerus in a chemically defined medium; such a concentration also inhibited cephalosporin production. Although Tris buffer was found to have detrimental effects on growth and ant
## Abstract Product inhibition of biological production systems is a widely observed phenomenon with prominent implications for the design and ultimately the success of biotechnological processes. In order to investigate whether such effects could limit the maximal concentrations in the production