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Influence of cyclooxygenase-2 on matrix mefalloproteinase expression in breast cancer

✍ Scribed by T. Barry; D. G. Healy; D. O’Hanlon; R. W. G. Watson; T. F. Gorey; J. M. Fitzpatrick; M. J. Kerin

Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
913 KB
Volume
171
Category
Article
ISSN
1863-4362

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## Abstract ## Introduction The cyclooxygenase‐2 (COX‐2), responsible for the conversion of arachidonic acid into prostaglandin (PG) E2, is known to increase intracellular cAMP and estrogen production in malignant breast tissue. The aromatase enzyme complex is responsible for local production of e