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Influence of C6 and CNS1 Brain Tumors on Methotrexate Pharmacokinetics in Plasma and Brain Tissue

✍ Scribed by Sylvain F. Dukic; Matthieu L. Kaltenbach; Tony Heurtaux; Guillaume Hoizey; Aude Lallemand; Richard Vistelle

Book ID
111601849
Publisher
Springer US
Year
2004
Tongue
English
Weight
96 KB
Volume
67
Category
Article
ISSN
0167-594X

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## Abstract The neurochemical environment of nontumorous white matter tissue was investigated in 135 single voxel spectra of β€œhealthy” white matter regions of 43 tumor patients and 129 spectra of 52 healthy subjects. Spectra were acquired with short TE and TR values. With the data of tumor patients