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Influence of B cells in liver fibrosis associated with hepatitis B virus harboring basal core promoter mutations

✍ Scribed by Mohamadkhani, Ashraf; Bastani, Faegh; Sotoudeh, Masoud; Sayehmiri, Kourosh; Shahnazari, Parisa; Montazeri, Ghodratollah; Poustchi, Hossein


Book ID
118763075
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
876 KB
Volume
84
Category
Article
ISSN
0146-6615

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The core promoter region of hepatitis B virus genomes regulates transcription of the precore and pregenomic mRNAs encoding hepatitis B e antigen (HBeAg) and core antigen that contain target epitopes for cytotoxic T lymphocytes. The prevalence and clinical significance of mutations in this region wer