## Abstract The existence of statistical associations between hepatitis Bβrelated acuteβonβchronic liver failure and both hepatitis B virus (HBV) genotype and mutations in the basal core promoter (BCP) and precore (PC) regions needs to be confirmed. A total of 322 patients with a chronic HBV infect
Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis
β Scribed by X. Ren; Z. Xu; Y. Liu; X. Li; S. Bai; N. Ding; Y. Zhong; L. Wang; P. Mao; F Zoulim; D Xu
- Book ID
- 108886403
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 116 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1352-0504
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Spontaneous mutations of hepatitis B virus (HBV) could influence the severity of liver disease. Since the basal core promoter (BCP) and the precore (Pc) regions are important for viral replication, these regions were examined for naturally occurring mutations and were correlated with the genotype, e
## Abstract The aim of this study was to determine whether mutations in the hepatitis B virus (HBV) genome are associated with the onset of acute on chronic liver failure (ACLF). For the longitudinal study, fullβlength HBV genomes were cloned and sequenced from four ACLF patients and compared with