Influence of aminoazo dyes on drug metabolism in rat liver
β Scribed by Baldwin, R W; Barker, C R
- Book ID
- 109833003
- Publisher
- Nature Publishing Group
- Year
- 1965
- Tongue
- English
- Weight
- 853 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0007-0920
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The influences of phenobarbital (PB) on enzymes of the carbohydrate metabolism in rat liver are examined during pre-and postnatal development. The following results are obtained: (1) PB generally increases G-6-Pase before and after birth. (2) Both the active and the inactive forms of phosphorylase a
## Abstract Two groups of male SpragueβDawley rats of different ages received a carcinogenic diet containing 0.06% dimethylaminoazobenzene (DAB). Out of a group of 4β to 6β weekβold rats, 20% developed hepatomas 31/2 months after the beginning of the diet, and after 10 months the percentage of tumo