## Abstract Morphine is frequently used to treat painful episodes associated with sickle cell disease (SCD) but may fail to provide adequate analgesia in many patients. This concise review focuses on unique disease related changes in physiologic variables associated with SCD that impacts pharmacoki
Inflammatory potential of neutrophils detected in sickle cell disease
โ Scribed by Aaron F.H. Lum; Ted Wun; Donald Staunton; Scott I. Simon
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 260 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0361-8609
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๐ SIMILAR VOLUMES
## Abstract Changes in several components of the clotting system are well documented in sickle cell disease (SCD) patients. However, whether the global hemostatic potential of these patients is altered is still unclear. Calibrated automated thrombogramยฎ method of thrombin generation (TG) was used t
Frequency of painful episodes in sickle-cell disease is considered to be related to clinical severity and possibly to other aspects of the disease. Measurements of frequency often include only hospital-related or more severe, longer-lasting episodes. Since painful episodes, however, may regularly oc