Inflammation as a causative factor in the aetiology of Parkinson's disease
β Scribed by P S Whitton
- Book ID
- 110009447
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 199 KB
- Volume
- 150
- Category
- Article
- ISSN
- 0007-1188
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## Abstract Multiple genes have been now identified as causing Parkinson's disease (PD). In 2003, two mutations were identified in exon 1 of the Nurr1 gene in 10 of 107 individuals with familial PD. To date, investigators have only focused on screening for these known mutations of the Nurr1 gene. A
## Abstract Parkinson's disease (PD) is a common neurodegenerative disorder caused by loss of dopaminergic neurons in the brainstem. Recent studies suggest that several genes may have a role in determining individual susceptibility to this disease, and the degradative enzyme monoamine oxidase (MAO)