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Environmental MPTP as a factor in the aetiology of Parkinson's disease?

✍ Scribed by B. L. Goodwin; G. C. Kite


Publisher
Springer
Year
1998
Tongue
English
Weight
115 KB
Volume
105
Category
Article
ISSN
1435-1463

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This is the first study to investigate the potential protective effects of the lipophilic kavapyrone (+/-)-kavain in the experimental MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) model of Parkinson's disease (PD). Male C57BL/6 mice were treated with (+/-)-kavain (50, 100, or 200 mg/kg i.p.) o