The completely revised second edition of this user-friendly and application-oriented overview of one-step biotransformations of industrial importance.
Based on extensive literature and patent research, this book is unique in arranging each process in a systematic way to allow for easy comparison. All the chapters have been rewritten, with all the processes updated and more than 30 new processes added. Each set of data is accompanied by key literature citations, supported by flow sheets where available, reduced to their significant elements. In addition, an extensive index classified by substrates, products, enzymes, and companies provides direct access to each process, organized according to enzyme class. Biotechnologists, biochemists, microbiologists, process engineers and those working in the chemical and biotechnological industries will find here all the significant parameters characterizing both the biotransformation and the process.Content:
Chapter 1 History of Industrial Biotransformations โ Dreams and Realities (pages 1โ36): Prof. Dr. Durda Vasic?Racki
Chapter 2 The Enzyme Classification (pages 37โ62): Dipl.?Chem. Christoph Hoh and Dr. Murillo Villela Filho
Chapter 3 Retrosynthetic Biocatalysis (pages 63โ91): Dr. Junhua Tao, Alan Pettman and Prof. Dr. Andreas Liese
Chapter 4 Optimization of Industrial Enzymes by Molecular Engineering (pages 93โ114): Dr. Thorsten Eggert
Chapter 5 Basics of Bioreaction Engineering (pages 115โ145): Dr. Nagaraj N. Rao, Dipl.?Chem. Stephan Lutz, Dr. Karsten Seelbach and Prof. Dr. Andreas Liese
Chapter 6 Processes: Oxireductases EC 1 (pages 147โ263): Prof. Dr. Andreas Liese, Dr. Karsten Seelbach, Dr. Arne Buchholz and Dr. Jurgen Haberland
Chapter 6 Processes: Transferases EC 2 (pages 264โ272): Prof. Dr. Andreas Liese, Dr. Karsten Seelbach, Dr. Arne Buchholz and Dr. Jurgen Haberland
Chapter 6 Processes: Hydrolases EC 3 ? EC 3.1.1.3 to EC 3.4.17.2 (pages 273โ349): Prof. Dr. Andreas Liese, Dr. Karsten Seelbach, Dr. Arne Buchholz and Dr. Jurgen Haberland
Chapter 6 Processes: Hydrolases EC 3 ? EC 3.4.21.4 to EC 3.8.X.X (pages 350โ446): Prof. Dr. Andreas Liese, Dr. Karsten Seelbach, Dr. Arne Buchholz and Dr. Jurgen Haberland
Chapter 6 Processes: Lyases EC 4 (pages 447โ503): Prof. Dr. Andreas Liese, Dr. Karsten Seelbach, Dr. Arne Buchholz and Dr. Jurgen Haberland
Chapter 6 Processes: Isomerases EC 5 (pages 504โ513): Prof. Dr. Andreas Liese, Dr. Karsten Seelbach, Dr. Arne Buchholz and Dr. Jurgen Haberland
Chapter 7 Quantitative Analysis of Industrial Biotransformation (pages 515โ520): Prof. Dr. Adrie J. J. Straathof