Biotransformations have developed into an important tool of organic synthesis and most synthetic sequences will benefit from the use of a biotransformation step. This volume completes the collection of biotransformations presented in the Biotechnology series. Volumes 8 a and b provide a comprehensive guide to the established and emerging uses of enzymes, each chapter is devoted to a single class of transformation.
The description of several bond forming reactions is followed by four chapters on structue and catalytic activity. Case studies of important industrial and synthetic applications round off the practical orientation of the book.
Content:
Chapter 1 Carbon?Carbon Bond Formation, Addition, Elimination and Substitution Reactions: 1 Carbon?Carbon Bond Formation Using Enzymes (pages 4β40): Anthony D. M. Curtis
Chapter 2 Lyases (pages 41β171): Jassem G. Mahdi and David R. Kelly
Chapter 3 Halocompounds (pages 173β220): Gary K. Robinson, Simon A. Jackman and Jane Stratford
Chapter 4 Phosphorylation (pages 221β241): Simon Jones
Chapter 5 Enzymes in Carbohydrate Chemistry: Formation of Glycosidic Linkages (pages 243β274): Sabine L. Flitsch and Gregory M. Watt
Chapter 6 Industrial Biotransformations (pages 276β294): Uwe T. Bornscheuer
Chapter 7 Regioselective Oxidation of Aminosorbitol with Gluconobacter oxydans, Key Reaction in the Industrial 1?Deoxynojirimycin Synthesis (pages 295β311): Michael Schedel
Chapter 8 Engineering Microbial Pathways for Amino Acid Production (pages 313β332): Ian G. Fotheringham
Chapter 9 Biotechnological Production of Natural Aroma Chemicals by Fermentation Processes (pages 333β350): Jurgen Rabenhorst
Chapter 10 Synthetic Applications of Enzyme?Catalyzed Reactions (pages 351β400): Jane McGregor?Jones
Chapter 11 Catalytic Antibodies (pages 402β490): George Michael Blackburn and Arnaud Garcon
Chapter 12 Synthetic EnzymesβArtificial Peptides in Stereoselective Synthesis (pages 491β517): Paul A. Bentley