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Induction of the Acrosome Reaction in Guinea Pig Spermatozoa by cGMP Analogues

✍ Scribed by J. Santos-Sacchi and Mildred Gordon


Book ID
124799386
Publisher
Rockefeller University Press.
Year
1980
Tongue
English
Weight
549 KB
Volume
85
Category
Article
ISSN
0021-9525

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Potentiation of the cGMP-induced Guinea
✍ Santos-Sacchi, Joseph ;Gordon, Mildred ;Williams, William L. πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 255 KB

## Abstract The addition of 8 bromo cGMP (10 mM) immediately (∼2 min) upon suspension of Guinea pig sperm in glucose‐free BWW medium induces a significant number of acrosome reactions within minutes. The simultaneous addition of micromolar concentrations of ZnCl~2~ (25–1000 ΞΌM) potentiates the cGMP