Induction of specific T cell immunity in patients with prostate cancer by vaccination with PSA146–154 peptide
✍ Scribed by Supriya Perambakam; Sigrun Hallmeyer; Samarth Reddy; Nadim Mahmud; Linda Bressler; Phillip DeChristopher; Delores Mahmud; Rafael Nunez; Jeffrey A. Sosman; David J. Peace
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 391 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Prostate stem cell antigen (PSCA) and prostate‐specific antigen (PSA) are overexpressed in most prostate cancers. PSCA‐ and PSA‐derived, HLA‐A2 binding peptides are specific targets for T‐cell responses __in vitro.__ A phase I/II trial was performed to demonstrate feasibility, safety an
## BACKGROUND. In this paper we describe our program for the immune monitoring of phase II participants given dendritic cell (DC)/prostate-specific membrane antigen (PSMA)-based immunotherapy, and we also present some initial findings. METHODS. Phase II subjects received six administrations of aut