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Induction of antiidiotypic immune response with autologous T-cell vaccine in patients with multiple sclerosis

✍ Scribed by I. P. Ivanova; V. I. Seledtsov; G. V. Seledtsova; S. V. Mamaev; A. V. Potyemkin; D. V. Seledtsov; V. A. Kozlov


Publisher
Springer US
Year
2008
Tongue
English
Weight
362 KB
Volume
146
Category
Article
ISSN
0007-4888

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## Abstract Earlier studies from several groups including ours have documented that patients with multiple sclerosis (MS) have over‐expression of activated T‐cells from specific TCR VΞ² families, including BV6S2/S5 (Kotzin et al. [1991] Proc. Natl. Acad. Sci. USA 88:9161–9165; Gold et al. [1997] J.