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Induction of cellular immune responses against carcinoembryonic antigen in patients with metastatic tumors after vaccination with altered peptide ligand-loaded dendritic cells

✍ Scribed by Jana Babatz; Christoph Röllig; Bärbel Löbel; Gunnar Folprecht; Michael Haack; Heinrich Günther; Claus-Henning Köhne; Gerhard Ehninger; Marc Schmitz; Martin Bornhäuser


Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
279 KB
Volume
55
Category
Article
ISSN
0340-7004

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Induction of carcinoembryonic antigen (c
✍ Smita K. Nair; Shelley Hull; Doris Coleman; Eli Gilboa; H. Kim Lyerly; Michael A 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 107 KB 👁 2 views

The application of dendritic cells (DC) to the active immunotherapy of cancer currently relies on the generation of potent DC capable of presenting tumor antigens such as carcinoembryonic antigen (CEA). It is unknown whether the T cells of patients with advanced malignancies can be reliably stimulat