✦ LIBER ✦

Induction of specific-locus and dominant lethal mutations in male mice by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)

✍ Scribed by U.H. Ehling; I.-D. Adler; J. Favor; A. Neuhäuser-Klaus

Book ID: 114071353
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 314 KB
Volume: 379
Category: Article
ISSN: 0027-5107
DOI: 10.1016/s0027-5107(97)00153-x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A toxicologic comparison of the potency

A toxicologic comparison of the potency and activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in mice and rats

✍ George R. Thompson; Robert E. Larson 📂 Article 📅 1972 🏛 Elsevier Science 🌐 English ⚖ 640 KB

Physiologic disposition of 1-(2-chloroet

Physiologic disposition of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (MeCCNU) in man

✍ Robert W. Sponzo; Vincent T. Devita; Vincent T. Oliverio 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 English ⚖ 466 KB 👁 2 views

The physiologic disposition of radioactive-labelled CCNU and MeCCNU was studied in patients receiving these drugs as part of their early clinical trial. CCNU was given orally in doses of 30-100 mg/m2 a n d MeCCNU in doses of 120-290 mg/m?. With both drugs, significant plasma levels of radioactivity

Reactions of 1,3-bis(2-chloroethyl)-1-ni

Reactions of 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in aqueous solution

✍ Weinkam, Robert J.; Lin, Huey-Shin 📂 Article 📅 1979 🏛 American Chemical Society 🌐 English ⚖ 779 KB

Relationship of 1,3-bis(2-chloroethyl)-1

Relationship of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) pharmacokinetics of uptake, distribution, and tissue/plasma partitioning in rat organs and intracerebral tumors

✍ V. A. Levin; P. A. Kabra; M. A. Freeman-Dove 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 828 KB

In vitro pharmacokinetics and pharmacody

In vitro pharmacokinetics and pharmacodynamics of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)

✍ Hiroko Ueda-Kawamitsu; Terence A. Lawson; Peter R. Gwilt 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 273 KB

Inhibition of human glutathione reductas

Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea : A crystallographic analysis

✍ P. Andrew KARPLUS; R. Luise KRAUTH-SIEGEL; R. Heiner SCHIRMER; Georg E. SCHULZ 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 592 KB