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Induction of protective antitumor activity of tumor lysate-pulsed dendritic cells vaccine in RM-1 prostate cancer mode

✍ Scribed by Danfeng Xu; Yushan Liu; Yi Gao; Xingang Cui; Jizhang Xing; Lei Yin; Yacheng Yao; Zhilian Min


Book ID
114335112
Publisher
Elsevier
Year
2009
Tongue
English
Weight
200 KB
Volume
24
Category
Article
ISSN
1000-1948

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## Abstract Cyclooxygenase‐2 (COX‐2) is a rate‐limiting enzyme in the synthesis of prostaglandins. It is over‐expressed in multiple cancers and has been associated with diminished tumor immunity. Dendritic cells (DCs) are considered candidates for cancer immunotherapy due to their ability to proces