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Enhancement of antitumor immunity of dendritic cells pulsed with heat-treated tumor lysate in murine pancreatic cancer

✍ Scribed by Han-Soo Kim; Yee Shin Choo; Taeseok Koo; Seungmin Bang; Tae Yun Oh; Jing Wen; Si Young Song

Book ID
108152279
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
208 KB
Volume
103
Category
Article
ISSN
0165-2478

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## Abstract Cyclooxygenase‐2 (COX‐2) is a rate‐limiting enzyme in the synthesis of prostaglandins. It is over‐expressed in multiple cancers and has been associated with diminished tumor immunity. Dendritic cells (DCs) are considered candidates for cancer immunotherapy due to their ability to proces