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Superior efficacy of dendritic cell-tumor fusion vaccine compared with tumor lysate-pulsed dendritic cell vaccine in colon cancer

✍ Scribed by John Y. Kao; Min Zhang; Chuan-Min Chen; Jian-Jun Chen


Book ID
108152253
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
180 KB
Volume
101
Category
Article
ISSN
0165-2478

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## Abstract Cyclooxygenase‐2 (COX‐2) is a rate‐limiting enzyme in the synthesis of prostaglandins. It is over‐expressed in multiple cancers and has been associated with diminished tumor immunity. Dendritic cells (DCs) are considered candidates for cancer immunotherapy due to their ability to proces