Induction of NF-κB, IκB-α, and iNOS in Rat Gastric Mucosa during Endotoxemia
✍ Scribed by Kenneth S. Helmer; Lily Chang; Yan Cui; David W. Mercer
- Book ID
- 115636631
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 116 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0022-4804
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In infectious diseases of the central nervous system astrocytes respond to inflammatory cytokines like tumor necrosis factor ␣ (TNF␣) by activation of the transcription factor NF-B, mediated by the proteolysis of its inhibitors IB␣ and IB. We studied the kinetics of NF-B induction by TNF␣ in primar
## Abstract Exposure to ultraviolet B (UVB) radiation is known to cause inflammatory tissue damage and skin cancer. One of the molecular links between inflammation and cancer is the eukaryotic transcription factor nuclear factor‐kappaB (NF‐κB), which is known to regulate expression of various pro‐i