Induction of immunity and tolerance in vitro by hapten protein conjugates. II. Carrier independence of the response to dinitrophenylated polymerized flagellin
β Scribed by Marc Feldmann
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- English
- Weight
- 903 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0014-2980
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## Abstract The immunogenicity and tolerogenicity of 2,4βdinitrophenyl (DNP) conjugates of levan, type 3 pneumococcal polysaccharide (SIII), dextran B512 and dextran B 1299 with different levels of substitution were assessed __in vivo__. It was confirmed that, as __in vitro__, conjugates with low e
## Abstract Tolerance induction of IgE antibodyβforming cells by dinitrophenylated levan (DNPβLE) conjugates was investigated in CBA mice. Antibody production was measured by passive coutaneous anaphylaxis on rat skin. Specific antibody neutralization was obtained with conjugates of different subst