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Induction of immunity and tolerance in vitro by hapten protein conjugates. II. Carrier independence of the response to dinitrophenylated polymerized flagellin

✍ Scribed by Marc Feldmann


Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
903 KB
Volume
2
Category
Article
ISSN
0014-2980

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Role of epitope density in the induction
✍ Catherine Desaymard; J. G. Howard πŸ“‚ Article πŸ“… 1975 πŸ› John Wiley and Sons 🌐 English βš– 481 KB πŸ‘ 2 views

## Abstract The immunogenicity and tolerogenicity of 2,4‐dinitrophenyl (DNP) conjugates of levan, type 3 pneumococcal polysaccharide (SIII), dextran B512 and dextran B 1299 with different levels of substitution were assessed __in vivo__. It was confirmed that, as __in vitro__, conjugates with low e

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## Abstract Tolerance induction of IgE antibody‐forming cells by dinitrophenylated levan (DNP‐LE) conjugates was investigated in CBA mice. Antibody production was measured by passive coutaneous anaphylaxis on rat skin. Specific antibody neutralization was obtained with conjugates of different subst