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Induction of cytochrome P-450E (P-450IA1) by 2,3,7,8-tetrachlorodibenzofuran (2,3,7,8-TCDF) in the marine fish scup (Stenotomus chrysops)

โœ Scribed by Mark E. Hahn; Bruce R. Woodin; John J. Stegeman


Book ID
119068139
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
231 KB
Volume
28
Category
Article
ISSN
0141-1136

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The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dioxin, produces a diverse set of biological responses which, in some cases, reflects the altered expression of specific genes. An intracellular receptor protein binds TCDD saturably and with high affinity and mediates several