๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

2,3,7,8-tetrachlorodibenzo-P-dioxin induces cytochrome P450IA1 enzyme activity by activating transcription of the corresponding gene

โœ Scribed by Amy E. Lusska; Keith W. Jones; Cornelis J. Elferink; Lena Wu; Emily S. Shen; Long-Ping Wen; James P. Whitlock Jr.

Book ID
118372184
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
575 KB
Volume
31
Category
Article
ISSN
0065-2571

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

2,3,7,8-Tetrachlorodibenzo-p-dioxin rece
2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors regulate transcription of the cytochrome P1-450 gene
โœ Linda K. Durrin; Phillip B. C. Jones; Joan M. Fisher; Donna R. Galeazzi; James P ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 534 KB

The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dioxin, produces a diverse set of biological responses which, in some cases, reflects the altered expression of specific genes. An intracellular receptor protein binds TCDD saturably and with high affinity and mediates several

Activation of cytochrome P450IA1 gene ex
Activation of cytochrome P450IA1 gene expression by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in wild-type and high-activity variant mouse hepatoma cells
โœ Margaret A. Hirst; Keith W. Jones; James P. Whitlock Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 666 KB

We analyzed the function of a DNA domain located upstream of the cytochrome P4501A1 gene in wild-type (Hepa lclc7) mouse hepatoma cells and in high-activityvariant (HAV) cells that overtranscribe the gene in response to the inducer 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Transfection experiments