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Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

✍ Scribed by Alvaro Puga; Sonya J Barnes; Ching-yi Chang; Huan Zhu; Kenneth P Nephew; Sohaib A Khan; Howard G Shertzer


Book ID
113994732
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
533 KB
Volume
59
Category
Article
ISSN
0006-2952

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✍ Hitoshi Ashida; Fumio Matsumura 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 319 KB 👁 1 views

To study the long-term effect of 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD) on the DNAbinding activity of nuclear transcription factors; a single dose of TCDD was injected intraperitoneally to male guinea pigs (1 lg/kg i.p.). The animals were killed after 1, 2, 10, 20, 28, and 40 days, and DNA-bindin