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Transcriptional control of human cytochrome P1-450 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human tissue culture cell lines

โœ Scribed by Thierry Cresteil; Anil K. Jaiswal; Howard J. Eisen

Book ID
115707614
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
649 KB
Volume
253
Category
Article
ISSN
0003-9861

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โœ Linda K. Durrin; Phillip B. C. Jones; Joan M. Fisher; Donna R. Galeazzi; James P ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 534 KB

The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dioxin, produces a diverse set of biological responses which, in some cases, reflects the altered expression of specific genes. An intracellular receptor protein binds TCDD saturably and with high affinity and mediates several