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Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: Insights into the measurement of hepatic cytochrome P450 1A2 induction*

✍ Scribed by Abraham, Klaus; Geusau, Alexandra; Tosun, Yalcin; Helge, Hans; Bauer, Steffen; Brockmöller, Jürgen


Book ID
111727934
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
173 KB
Volume
72
Category
Article
ISSN
0009-9236

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The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dioxin, produces a diverse set of biological responses which, in some cases, reflects the altered expression of specific genes. An intracellular receptor protein binds TCDD saturably and with high affinity and mediates several