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Effect of a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on hepatic and extrahepatic cytochrome P-450 IA induction in the Swiss mouse

✍ Scribed by L.E. Beebe; L.W. Fornwald; L.M. Anderson


Book ID
116079018
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
187 KB
Volume
25
Category
Article
ISSN
0045-6535

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## Abstract The induction response of cytochrome P‐450‐dependent enzyme activities to a single low (5 nmol/kg) or high (50 nmol/kg, intraperitoneal [ip] dose of TCDD was examined in liver and lung homogenates over a 12‐week time course in an outbred, Ah‐responsive strain of mice (National Institute