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Induction of CAD gene amplification by restriction endonucleases in V79,B7 Chinese hamster cells

โœ Scribed by P. Cavolina; C. Agnese; A. Maddalena; G. Sciandrello; A. Di Leonardo

Book ID
113255208
Publisher
Elsevier Science
Year
1989
Weight
267 KB
Volume
225
Category
Article
ISSN
0165-7992

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Spontaneous phenotypic revertants of hypoxanthine phosphoribosyl-transferase (HPRT) temperature-sensitive V79 Chinese hamster cells were selected by plating a temperature-sensitive mutant in HAT medium at 39OC. The incidence of such revertants was approximately 2 x per cell. The majority of the reve