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Induction of apoptosis with mitochondrial membrane depolarization by a glycyrrhetinic acid derivative in human leukemia K562 cells

✍ Scribed by Gao, Zhenbei; Kang, Xiao; Hu, Jun; Ju, Yong; Xu, Chuanlian


Book ID
113064195
Publisher
Springer
Year
2012
Tongue
English
Weight
596 KB
Volume
64
Category
Article
ISSN
0920-9069

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## Abstract Methyl 2‐cyano‐3,11‐dioxo‐18β‐olean‐1,12‐dien‐30‐oate (CDODA‐Me) is a synthetic triterpenoid derived from glycyrrhetinic acid, a bioactive phytochemical in licorice, CDODA‐Me inhibits growth of Panc1 and Panc28 pancreatic cancer cell lines and activates peroxisome proliferator‐activated