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Induction of apoptosis in human leukemia K562 cells by cardiotoxin III

โœ Scribed by Sheng-Huei Yang; Mei-Chin Lu; Ching-Ming Chien; Chia-Houg Tsai; Yu-Jhang Lu; Tzyh-Chyuan Hour; Shinne-Ren Lin

Book ID
116717931
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
154 KB
Volume
76
Category
Article
ISSN
0024-3205

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Cardiotoxin III-induced apoptosis is med
Cardiotoxin III-induced apoptosis is mediated by Ca2+-dependent caspase-12 activation in K562 cells
โœ Sheng-Huei Yang; Ching-Ming Chien; Long-Sen Chang; Shinne-Ren Lin ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 289 KB ๐Ÿ‘ 1 views

## Abstract Cardiotoxin III (CTX III), a basic polypeptide with 60 amino acid residues isolated from __Naja naja atra__ venom, has been reported to have anticancer activity. When K562 cells were treated with CTX III, cytosolic calcium concentration was rapidly and persistently increased. This CTX I