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Induction of anergy in resting human T lymphocytes by immobilized anti-CD3 antibodies

✍ Scribed by Hans Wolf; Yvonne Müller; Sibylle Salmen; Wolfgang Wilmanns; Gundram Jung


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
936 KB
Volume
24
Category
Article
ISSN
0014-2980

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The proliferation of autologous tumor-reactive cytotoxic T lymphocytes (CTL), induced by autologous mixed lymphocyte tumor-cell culture, was remarkably enhanced by activation with immobilized anti-CD3 monoclonal antibody (MAb) and interleukin-2 (IL-2), as compared with IL-2 alone. The activated CTL