✦ LIBER ✦

Inducible gene expression systems for higher eukaryotic cells

✍ Scribed by Manfred Gossen; Angelika L Bonin; Sabine Freundlieb; Hermann Bujard

Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 475 KB
Volume: 5
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(94)90067-1

No coin nor oath required. For personal study only.

✦ Synopsis

Of the wide variety of regulatory systems that have been developed to control gene expression in higher eukaryotes, those utilizing elements from prokaryotic systems presently achieve the highest specificity. In particular, systems based on the repressor/operator elements of an Escherichia coil tetracycline resistance operon appear broadly applicable. During the past year, the usefulness of these systems has been demonstrated not only at the cellular level, but also at the organismal level (i.e. in transgenic animals and plants).

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