✦ LIBER ✦

Inducers of the heat shock response stimulate phospholipase C and phospholipase A2 activity in mammalian cells

✍ Scribed by Stuart K. Calderwood; Mary Ann Stevenson

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 977 KB
Volume: 155
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1041550205

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Docosahexaenoic acid decreases phospholi

Docosahexaenoic acid decreases phospholipase A2 activity in the neurites/nerve growth cones of PC12 cells

✍ Rex E. Martin 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB 👁 1 views

Docosahexaenoic acid (DHA) accumulates in nerve growth cones (NGC) during perinatal development and it is neuroprotective in ischemia. Because the phospholipases A 2 (PLA 2 ) are present in NGC and these enzymes function in both ischemia and longterm potentiation, the relationship between DHA and PL

Interaction between heat shock and inter

Interaction between heat shock and interleukin 6 stimulation in the acute-phase response of human hepatoma (HepG2) cells

✍ Jens O. Karlsson; Martin L. Yarmush; Mehmet Toner 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 316 KB

Two characteristic elements of the acute-phase response are an altered pattern of circulating hepatic proteins and fever. Whereas a fever-induced heat shock response could affect expression of acute-phase proteins in the liver, the effects of a modest temperature increase on protein secretion in int

Insulin-like growth factor-I-dependent s

Insulin-like growth factor-I-dependent stimulation of nuclear phospholipase C-β1 activity in Swiss 3T3 cells requires an intact cytoskeleton and is paralleled by increased phosphorylation of the phospholipase

✍ Alberto M. Martelli; Lucio Cocco; Renato Bareggi; Giovanna Tabellini; Riccardo R 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 1 views

Swiss 3T3 mouse fibroblasts were exposed to 10 microM colchicine to disrupt microtubules, then stimulated with insulin-like growth factor-I. Immunoprecipitation experiments showed that insulin-like growth factor-I receptor and insulin receptor substrate-1 were tyrosine phosphorylated to the same ext

Surface roughness modulates the response

Surface roughness modulates the response of MG63 osteoblast-like cells to 1,25-(OH)2D3 through regulation of phospholipase A2 activity and activation of protein kinase A

✍ Lohmann, C. H. ;Sagun, R. ;Sylvia, V. L. ;Cochran, D. L. ;Dean, D. D. ;Boyan, B. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 673 KB

Implant surface roughness influences osteoblast proliferation, differentiation, and local factor production. Moreover, the responsiveness of osteoblasts to systemic hormones such as 1,25-(OH) 2 D 3 is altered by the effects of surface roughness; on the roughest Ti surfaces the effects of roughness a

Regulation of the heat-shock response by

Regulation of the heat-shock response by interferon in mouse L cells

✍ M. F. Dubois; V. Mezger; M. Morange; C. Ferrieux; P. Lebon; O. Bensaude 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 885 KB

Interferon (IFN) is not able to induce heat-shock protein (HSP) synthesis. However IFN pretreatment of mouse L cells has been shown to enhance the decrease of overall protein synthesis which follows a heat shock, and to stimulate the accumulation of HSPs. We show here that the synthesis of a protein

The cold-shock response in cultured mamm

The cold-shock response in cultured mammalian cells: Harnessing the response for the improvement of recombinant protein production

✍ Mohamed B Al-Fageeh; Rosalyn J Marchant; Martin J Carden; C Mark Smales 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 124 KB 👁 1 views

## Abstract There are a growing number of reports on the sub‐physiological temperature culturing (<37°C) of mammalian cells for increased recombinant protein yield, although the effect is variable between cell lines, expression systems, and the product of interest. What is becoming clear is that ex