𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Induced Synthesis of O6-Methylguanine-DNA Methyltransferase in Rat Hepatoma Cells Exposed to DNA-damaging Agents

✍ Scribed by Fukuhara, Masao ;Hayakawa, Hiroshi ;Sakumi, Kunihiko ;Sekiguchi, Mutsuo


Book ID
108579546
Publisher
Wiley (Blackwell Publishing)
Year
1992
Tongue
English
Weight
374 KB
Volume
83
Category
Article
ISSN
0910-5050

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Contribution of O6-methylguanine-DNA met
✍ Michael S. Bobola; A. Blank; Mitchel S. Berger; John R. Silber πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 997 KB

## Abstract The DNA repair protein __O__^6^‐methylguanine‐DNA methyltransferase (MGMT) has been implicated in resistance of human brain tumors to alkylating agents. We observed that 14 human medulloblastoma‐ and gliomaderived cell lines differ in sensitivity to the methylating agent __N__‐methyl‐__

Expression of human O6-methylguanine-DNA
✍ Zining Wu; Chung-Leung Chan; Alan Eastman; Edward Bresnick πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 692 KB

We have constructed a plasmid in which the expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA is driven by the Rous sarcoma virus promoter sequence. Transfection of this plasmid into Chinese hamster ovary (CHO) cells results in expression of MGMT and in cellular resistance to N-m