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Indoleamine 2,3-dioxygenase–expressing antigen-presenting cells and peripheral T-cell tolerance

✍ Scribed by von Bubnoff, Dagmar; Hanau, Daniel; Wenzel, Joerg; Takikawa, Osamu; Hall, Brian; Koch, Susanne; Bieber, Thomas

Book ID
119491074
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
194 KB
Volume
112
Category
Article
ISSN
1097-6825

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Inhibition of allogeneic T-cell responses by dendritic cells expressing transduced indoleamine 2,3-dioxygenase
✍ Naoko Funeshima; Masayuki Fujino; Yusuke Kitazawa; Yuko Hara; Yoshiaki Hara; Kou 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 222 KB

## Abstract ## Background Indoleamine 2,3‐dioxygenase (IDO) is an enzyme involved in the catabolism of tryptophan and has been shown to prevent rejection of the fetus during pregnancy by inhibiting alloreactive T cells. ## Methods In this study we investigated dendritic cells (DCs) that are tran