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Indoleamine 2,3-Dioxygenase Gene in Pre-eclampsia

✍ Scribed by Viroj Wiwanitkit

Book ID: 111270372
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 46 KB
Volume: 64
Category: Article
ISSN: 8755-8920
DOI: 10.1111/j.1600-0897.2010.00862.x

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## Abstract Human indoleamine 2,3‐dioxygenase (hIDO), a monomeric heme enzyme, catalyzes the oxidative degradation of L‐tryptophan (L‐Trp) and other indoleamine derivatives. Its activity follows typical Michaelis–Menten behavior only for L‐Trp concentrations up to 50 μM; a further increase in the c