Indirect determination of octanol-water partition coefficients by microemulsion electrokinetic chromatography
✍ Scribed by S.J. Gluck; M.H. Benkö; R.K. Hallberg; K.P. Steele
- Book ID
- 107786056
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 356 KB
- Volume
- 744
- Category
- Article
- ISSN
- 1873-3778
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Microemulsion electrokinetic chromatography (MEEKC) was assessed as a tool for determination of octanol-water partition coefficients using 34 solutes encompassing 8 carbonate esters. It was confirmed that microemulsions containing 1.44-2.88% w/w SDS, 6.49% w/w 1-butanol, and 0.82% w/w n-heptane cons
## Abstract Micellar electrokinetic chromatography (MEKC) was evaluated as a new technique for the rapid estimation of octanol‐water partition coefficient (log__K__~ow~). Retention measurements for more than 40 reference pesticides with varied structural characteristics and hydrophobicity were carr
The use of liquid chromatography to estimate octanol-water partition coefficients, log k,,, has been demonstrated. The capacity factor with a mobile phase of 100% water, k,, has been found to be a useful chromatographic parameter. Values of k, were derived from a computer software package (Hipac-G),