Analysis of anticancer platinum(II)-complexes by microemulsion electrokinetic chromatography: Separation of diastereomers and estimation of octanol-water partition coefficients

Determination of octanol-water partition

Determination of octanol-water partition coefficients for carbonate esters and other small organic molecules by microemulsion electrokinetic chromatography

✍ Jesper Østergaard; Steen Honoré Hansen; Claus Larsen; Christian Schou; Niels H. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 119 KB 👁 1 views

Microemulsion electrokinetic chromatography (MEEKC) was assessed as a tool for determination of octanol-water partition coefficients using 34 solutes encompassing 8 carbonate esters. It was confirmed that microemulsions containing 1.44-2.88% w/w SDS, 6.49% w/w 1-butanol, and 0.82% w/w n-heptane cons