Independent Regulation of Transforming Growth Factor-β1 Transcription and Translation by Glucose and Platelet-Derived Growth Factor
✍ Scribed by Donald Fraser; Lalage Wakefield; Aled Phillips
- Book ID
- 117022123
- Publisher
- American Society for Investigative Pathology
- Year
- 2002
- Tongue
- English
- Weight
- 491 KB
- Volume
- 161
- Category
- Article
- ISSN
- 0002-9440
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📜 SIMILAR VOLUMES
We have examined the ability of transforming growth factor-pl (TGF-p1) and platelet-derived growth factor-BB (PDGF-BB) to regulate the expression of various integrins in cultured rabbit vascular smooth muscle cells (SMC). We found that expression of the a,p3 integrin complex was induced by both grow
## Abstract PTEN is a critical tumor suppressor gene mutated frequently in various human cancers. Previous studies have showed that PTEN mRNA expression is down‐regulated by TGF‐β1 in various cell lines. In present study, we have found that TGF‐β1 down‐regulates PTEN mRNA and protein expression in