𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Differential regulation of transforming growth factor-β receptors type I and II by platelet-derived growth factor in human dermal fibroblasts

✍ Scribed by J. Czuwara-Ladykowska; E.A. Gore; D.A. Shegogue; E.A. Smith; M. Trojanowska


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
485 KB
Volume
145
Category
Article
ISSN
0007-0963

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Regulation of fibrogenic/fibrolytic gene
✍ Masatoshi Jinnin; Hironobu Ihn; Yoshihiro Mimura; Yoshihide Asano; Kenichi Yaman 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 257 KB 👁 1 views

## Abstract Platelet‐derived growth factor (PDGF) is a potent mitogenic and chemotactic cytokine, and PDGF‐C is a novel growth factor belonging to the PDGF family. In this study, to determine whether this growth factor can contribute to fibrosis and tissue remodeling, we examined the effect of PDGF

Density-dependent inhibitory effect of t
✍ Y. Paulsson; C. Karlsson; C.-H. Heldin; B. Westermark 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 812 KB

## Abstract We have previously found that transforming growth factor‐β1 (TGF‐β1) inhibits the mitogenic activity of platelet‐derived growth factor (PDGF) in cultures of human neonatal fibroblasts in a density‐dependent fashion. In the present investigation we determined the effect of TGF‐β1 on the

Mitogenic effect of transforming growth
✍ Osamu Ishikawa; E. Carwile LeRoy; Maria Trojanowska 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 694 KB

## Abstract Platelet‐derived growth factor (PDGF) and transforming growth factor β (TGF‐β), potent modulators of mesenchymal cell growth and differentiation, are often colocalizable in vivo. Previous in vitro studies in fibroblastic cell lines have shown variable, even antagonistic effects of TGF‐β

Transforming growth factor-β1 regulates
✍ Massimo Pinzani; Alessandra Gentilini; Alessandra Caligiuri; Raffaella De Franco 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 901 KB

Activated liver fat-storing cells (FSC) are known to play a key role in the development of liver fibrosis. An important element in FSC activation process is the increased expression of receptors for platelet-derived growth factor (PDGF), a potent mitogen for FSC. The aim of the present study was to

Transforming growth factor-β receptor ex
✍ Betty Y. Y. Tam; Anie Philip 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 388 KB 👁 1 views

Fibroblasts play a critical role in wound repair and in the development of fibrotic diseases, and transforming growth factor-beta (TGF-beta) has been shown to profoundly modulate fibroblast function. However, there is limited information on the TGF-beta receptor types, isoform specificity, and compl