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Increasing prevalence of HIV-1 protease inhibitor-associated mutations correlates with long-term non-suppressive protease inhibitor treatment

✍ Scribed by R.M. Kagan; P.K. Cheung; T.K. Huard; M.A. Lewinski


Book ID
113457290
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
454 KB
Volume
71
Category
Article
ISSN
0166-3542

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## Abstract This study aimed at identifying HIV‐1 protease amino acid changes associated with protease inhibitor (PI) exposure and susceptibility. New amino acid substitutions were correlated with the number of experienced PIs, reaching statistical significance only for those at positions 3, 44, an